Thursday, January 24, 2019
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GLOBAL FUND to Fight AIDS, Tuberculosis and Malaria

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Drug Resistant Tuberculosis

imagesInstitute of Human Virology Nigeria (IHVN) was selected in 2011 as the Principal Recipient of the Global Fund to Fight AIDS, Tuberculosis and Malaria Round 9 Multi-drug Resistant Tuberculosis (MDR-TB) Grant. The goal of the grant is to strengthen MDR-TB prevention and control in Nigeria. IHVN is partnering with the National Tuberculosis and Leprosy Control Program (NTBLCP) of the Federal Ministry of Health (FMoH) and other stakeholders in the implementation of the scale-up of the Programmatic Management of Drug-Resistant TB (PMDT). On receiving the Grant, the NTBLCP (also a Sub-Recipient to the grant), set up a coordinating mechanism for the MDR-TB program and supported IHVN and other partners in setting up implementation structures for intervention activities. Phase 1 recorded a grant rating of A1, with 168 patients commenced on treatment across seven treatment centres that were activated.

In Phase 2, the activities supported by the grant include infrastructural upgrade, supply of equipment and maintenance of some treatment centres and reference laboratories; and supply of reagents, consumables and data collection tools. The Institute also carried out capacity building for treatment centres, laboratory and state TB staff on service provision and data collection; sputum transportation logistics nationwide to increase case detection; strengthened routine surveillance for Drug-Resistant Tuberculosis (DR-TB) at all levels; and established and supported State MDR-TB Teams for strengthening oversight and supervision of patients

In 2015, IHVN was again selected by the Country Coordinating Mechanism of Nigeria as a Principal Recipient to implement the Global Fund New Funding Model (NFM) MDR TB grant. The current grant aims to reduce the DR-TB burden by complementing and accelerating the ongoing activities implemented by the Nigerian government and partners, in the single stream funding, through the Global Fund New Funding Model Grant.

Major task includes scaling up the activities in the round 9 Grant to improve accessibility to DR-TB diagnosis, care and treatment services. New activities in the NFM DR-TB grant include; LGA team trainings, decentralization of outpatient services for the DR-TB patients, development of structured adherence program for DR-TB, development of Logistic Management Information Systems for laboratories, support for electronic data management through the e-TB manager and GX Alert Software, maintenance of GeneXpert machines, procurement and distribution of GeneXpert cartridges, procurement of basic emergency equipment for treatment centers to manage critically ill patients and improve treatment outcome, provision of solar-powered refrigerators for sample storage to reduce sample wastage.

With support from the Global Fund and other partners, there have been 149,569 presumptive cases for DR-TB that tested for DR-TB between June 2011 and September 2017. About 7,300 Drug-Resistant TB Cases (RR-TB and or MDR-TB) cases were notified between July 2011 and March 2018. Also 2,510 service providers have been trained in areas including, clinical and programmatic management of DR-TB, laboratory and laboratory techniques for TB culture, DST and Line Probe Assay, DR-TB recording and reporting tools and data management, pharmaceutical practices and Logistic Management Information System and Community support for DR-TB patients. More than 4,790 people received second-line treatment for drug-resistant tuberculosis between July 2011 and March 2018. The treatment centres providing DR-TB services are:

  1. Abubakar Tafawa Balewa University Teaching Hospital, Bauchi State
  2. Jos University Teaching Hospital, Plateau State
  3. University College Hospital, Ibadan (UCH), Oyo State
  4. Government Chest Hospital, Jericho, Ibadan, Oyo State
  5. University of Uyo Teaching Hospital, Uyo, (UUTH), Akwa-Ibom State
  6. University of Port Harcourt Teaching Hospital, Port Harcourt (UPTH). Rivers State
  7. Dr. Lawrence Henshaw Memorial Hospital, Calabar, Cross River State
  8. National Tuberculosis and Leprosy Training Center, Zaria (NTBLTC), Kaduna State
  9. Infectious Diseases Hospital, Kano State
  10. Sacred Hearts Hospital, Abeokuta, Ogun State
  11. Federal Medical Center Owerri, Imo State
  12. State Specialist Hospital, Sokoto, Sokoto State
  13. State Specialist Hospital Jalingo, Taraba
  14. St. Vincent Alaide Benue State
  15. General Hospital Iwo, Osun State
  16. Chest Hospital Jericho Ibadan Extremely Drug-Resistant TB Treatment Center
  17. Nnamdi Azikiwe University Teaching Hospital, Neni, Anambra State
  18. Federal Medical Center Umuahia, Abia State
  19. Federal Medical Center Yola, Adamawa State
  20. ERCC Alushi, Nasarawa State
  21. Kogi State University Teaching Hospital Anyigba, Kogi State
  22. Mile 4 Hospital Abakaliki, Ebonyi State
  23. Mainland Hospital Yaba, Lagos State
  24. King Fahd Hospital Zamfara State
  25. Infectious Diseases Hospital, Zambuk, Gombe State
  26. Specialist Hospital, Sobi, Kwara State
  27. Infectious Diseases Hospital, Akure, Ondo State (State Hospital Akure Annex).
  28. General Hospital Hadejiya, Jigawa

The currently operational TB Reference Laboratories are:

  1. National Institute for Medical Research Lagos State  - National
  2. National Tuberculosis Leprosy Training Center DR-TB Ward; Kaduna State- National
  3. University College Hospital Ibadan- Zonal
  4. Aminu Kano Teaching Hospital Kano State - Zonal
  5. Dr. Lawrence Henshaw Memorial Hospital Calabar Cross Rivers State – Zonal
  6. Zankli Hospital, Abuja, Federal Capital Territory - Zonal
  7. Jos University Teaching Hospital, Plateau State – Zonal
  8. University of Port Harcourt Teaching Hospital, Rivers State – Zonal
  9. State Hospital Amachara, Abia State
  10. Federal Medical Centre Yola, Adamawa State

In addition, IHVN partners with the following International Federation of Anti-Leprosy Associations (ILEP); (German Leprosy Relief Association (GLRA), Netherlands Leprosy Relief (NLR), Damien Foundation Belgium (DFB), The Leprosy Mission of Nigeria (TLMN) and Health Alive Foundation for state and community level activities.


The Institute of Human Virology Nigeria (IHVN) implemented the Global Fund Malaria program, as a Sub-Recipient to the National Malaria Elimination Program (NMEP) between 2009 and 2016.

Components of malaria control interventions were supported through selected public health facilities in 13 States - Katsina, Ogun, Kwara, Gombe, Akwa-Ibom, Kano, Kaduna, Borno, Kebbi, Plateau, Kogi, Benue and Jigawa States. Cumulatively, 417 public health facilities across 291 Local Government Areas (LGAs) were supported to deliver free prompt and effective malaria services in their various communities.


IHVN is a sub-recipient to FHI 360 implementing the Global Fund HIV New Funding Model (NFM) grant and providing services in the areas of HIV Testing Services (HTS), prevention of mother-to-child transmission (PMTCT), anti-retroviral treatment (ART) and TB/HIV services in Adamawa, Bauchi, Benue, Kano, Nasarawa, Ogun, Plateau, Taraba and Yobe states and the Federal Capital Territory. 

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 The Institute of Human Virology, Nigeria AITRP Training     Programmes are supported and funded by the Fogarty International Center.

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