The Evaluation of the Therapeutic Effectiveness of Dolutegravir-Based First-Line Regimen in Children and Adolescents Infected with HIV-1 in North Central Nigeria (DRESH) study aims to evaluate the effectiveness of DTG-based first line regimen in children and adolescents living with HIV who have been exposed on the regimen for a minimum of 12 months in the North Central region of…
DRESH Project
The Evaluation of the Therapeutic Effectiveness of Dolutegravir-Based First-Line Regimen in Children and Adolescents Infected with HIV-1 in North Central Nigeria (DRESH) study aims to evaluate the effectiveness of DTG-based first line regimen in children and adolescents living with HIV who have been exposed on the regimen for a minimum of 12 months in the North Central region of Nigeria.
The project is to find a pattern of detectable viral load among the study population in the selected study sites, assess the prevalence of drug resistance, and identify the type of selected mutations among the participants with VL above 1000 copies per ml after 12 months of treatment and identify the factors associated with treatment failure among the study population.
The study is being implemented in – the University of Abuja Teaching Hospital, Garki Hospital, Maitama District Hospital, Daughters of Charity Hospital, Gwarimpa General Hospital, Wuse General Hospital, Lugbe Primary Health Center, Asokoro District Hospital, and Nyanya General Hospital.
- Principal Investigator: Dr. Sophia Osawe
- Project Funders and collaborators: The West African Network for TB, AIDS and Malaria
(WANETAM) - via EDCTP funding
- Project Duration: 2023-2025