The Resilient HIV Implementation Science with Sexual and Gender Minority Youths using Evidence (RISE) project intends to adapt the HMP app towards improving HIV Prevention and Care among the Sexual and Gender Minority (SGM) youth aged 15-24.
RISE
The Resilient HIV Implementation Science with Sexual and Gender Minority Youths using Evidence (RISE) project intends to adapt the HMP app towards improving HIV Prevention and Care among the Sexual and Gender Minority (SGM) youth aged 15-24. It focuses on improving utilization of Pre-Exposure Prophylaxis and Antiretroviral Treatment specifically targeting young men who have sex with men (YMSM) and young transgender women (YTW). RISE is a multi-country study with implementation presence in Nigeria, Zambia, Kenya, and Malawi.
The project objectives include:
- Coordinating collaborative coalition between clinical research performing sites (CRPSs), community-based HIV service providers (CBSPs), youth advisory boards (YABs), and health ministries to maximize reach.
- Adapt the HMP app and assess system-level readiness to integrate HMP, a digital health intervention to address the PHCC among SGM youth, guided by the Consolidated Framework for Implementation Research (CFIR).
The study is a Phase III randomized control trial utilizing a Type 2 effectiveness-implementation hybrid design. A total of 750 participants will be randomly assigned to the HMP exposure while the other 750 participants will have delayed access to HMP. The study will enroll a total of 1,500 eligible participants within 24 months, and the randomization will occur at study enrollment.